Krievi arî grasâs atslçgt gçnu
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13.06.2019
Krievu biologs Deniss Rebrikovs intervijâ þurnâlam Nature pastâstîja, ka ir gatavs modificçt cilvçka gçnu un veikt embriju implantâciju. Zinâtnieks ir nobriedis veikt eksperimentu jau ðajâ gadâ, ja saòems atbilstoðu atïauju. Eksperimentâ paredzçts "atslçgt" gçnu, kas kodç olbaltumvielas, kuras ïauj HIV iekïût organisma ðûnâs.
Lai implantçtu embrijus, kam rediìçti gçni, biologs plâno modificçt gçnu CCR5, pie kura strâdâjis arî íînieðu biologs He Czankujs, kurð 2018. gada novembrî paziòoja par pirmo ìençtiski modificçto bçrnu radîðanu.
Pçc Rebrikova vârdiem, viòa gçna modificçðanas metode bûs mazâk riskanta un vairâk çtiski pamatota.
Eksperimenta veikðanas iespçjamîba zinâtniekiem izraisîjusi vairâkus jautâjumus. Piemçram, virkne speciâlistu uzskata, ka vçl nav izstrâdâta atbilstoða tehnoloìija. Tâpat nopietnus iebildumus rada eksperimenta çtiskâ puse.
Deniss Rebrikovs ir Kulakova vârdâ nosauktâ Dzemdniecîbas, ginekoloìijas un perinatoloìijas nacionâlâ medicînas centra gçnu rediìçðanas laboratorijas vadîtâjs..
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Source: Nature | «Russian biologist plans more CRISPR-edited babies» | https://www.nature.com/articles/d41586-019-01770-x |
<... The proposal follows a Chinese scientist who claimed to have created twins from edited embryos last year.
A Russian scientist says he is planning to produce gene-edited babies, an act that would make him only the second person known to have done this. It would also fly in the face of the scientific consensus that such experiments should be banned until an international ethical framework has agreed on the circumstances and safety measures that would justify them.
Molecular biologist Denis Rebrikov has told Nature he is considering implanting gene-edited embryos into women, possibly before the end of the year if he can get approval by then. ...>
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